Edward Chu Selected Research

Microsatellite Instability

12/2018	Recent Advances in the Clinical Development of Immune Checkpoint Blockade Therapy for Mismatch Repair Proficient (pMMR)/non-MSI-H Metastatic Colorectal Cancer.
11/2002	Lack of benefit of 5-fluorouracil-based adjuvant chemotherapy in colorectal cancer with microsatellite instability.

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Edward Chu Research Topics

Disease

63	Neoplasms (Cancer) 07/2023 - 07/2003
44	Colorectal Neoplasms (Colorectal Cancer) 03/2024 - 01/2000
17	Colonic Neoplasms (Colon Cancer) 12/2021 - 08/2003
4	Diarrhea 01/2018 - 04/2009
3	Chronic Disease (Chronic Diseases) 11/2021 - 01/2021
3	Thrombocytopenia (Thrombopenia) 12/2019 - 01/2017
3	Anemia 01/2017 - 05/2006
3	Vomiting 01/2017 - 04/2009
3	Fatigue 01/2017 - 05/2006
2	Breast Neoplasms (Breast Cancer) 07/2023 - 04/2023
2	Triple Negative Breast Neoplasms 04/2023 - 01/2022
2	Neutropenia 12/2019 - 04/2009
2	Pancreatitis 01/2019 - 02/2014
2	Adenocarcinoma 01/2019 - 01/2018
2	Head and Neck Neoplasms (Head and Neck Cancer) 01/2019 - 04/2006
2	Microsatellite Instability 12/2018 - 11/2002
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2018 - 10/2012
2	Vulvar Neoplasms (Vulvar Cancer) 11/2017 - 01/2017
2	Nausea 01/2017 - 04/2009
2	Leukopenia 01/2017 - 01/2017
2	Renal Cell Carcinoma (Grawitz Tumor) 01/2017 - 02/2015
2	Hemorrhage 02/2014 - 03/2011
2	Leukemia 07/2013 - 11/2008
2	Fibrosis (Cirrhosis) 07/2012 - 01/2012
1	Colitis 03/2024
1	Lung Neoplasms (Lung Cancer) 07/2023
1	Neoplasm Metastasis (Metastasis) 07/2023
1	Polyps 02/2023
1	Adenoma (Adenomas) 02/2023
1	Carcinogenesis 02/2023
1	Cancer Pain 01/2022

Drug/Important Bio-Agent (IBA)

15	Fluorouracil (Carac)FDA LinkGeneric 01/2019 - 07/2003
9	Capecitabine (Xeloda)FDA Link 12/2021 - 04/2005
7	Irinotecan (Camptosar)FDA LinkGeneric 01/2018 - 04/2005
6	Oxaliplatin (Eloxatin)FDA LinkGeneric 12/2021 - 04/2005
6	PHY 906IBA 01/2019 - 10/2009
5	veliparibIBA 04/2023 - 01/2017
5	Cytotoxins (Cytolysins)IBA 12/2019 - 04/2005
4	Cisplatin (Platino)FDA LinkGeneric 07/2023 - 01/2017
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 04/2006
4	Bevacizumab (Avastin)FDA Link 10/2021 - 05/2004
4	3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine)IBA 11/2020 - 01/2017
4	Small Interfering RNA (siRNA)IBA 04/2013 - 02/2004
4	Thymidylate SynthaseIBA 01/2011 - 11/2001
4	Cetuximab (Erbitux)FDA Link 12/2010 - 02/2004
4	ErbB Receptors (EGF Receptor)IBA 10/2007 - 02/2003
3	Paclitaxel (Taxol)FDA LinkGeneric 04/2023 - 01/2017
3	Proteins (Proteins, Gene)FDA Link 01/2023 - 07/2007
3	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022 - 01/2017
3	ElectrolytesIBA 10/2021 - 01/2017
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2017 - 04/2005
2	Imatinib Mesylate (Gleevec)FDA Link 07/2023 - 01/2014
2	Carboplatin (JM8)FDA LinkGeneric 04/2023 - 12/2019
2	Messenger RNA (mRNA)IBA 02/2023 - 01/2023
2	2-bromolysergic acid diethylamide (BOL)IBA 01/2023 - 01/2019
2	AntigensIBA 01/2022 - 10/2007
2	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 12/2019 - 01/2017
2	regorafenibIBA 01/2019 - 03/2015
2	Leucovorin (Folinic Acid)FDA Link 01/2018 - 10/2010
2	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 11/2017 - 01/2017
2	Phosphotransferases (Kinase)IBA 11/2017 - 01/2017
2	DNA (Deoxyribonucleic Acid)IBA 11/2017 - 05/2003
2	DeoxyribonucleotidesIBA 01/2017 - 08/2011
2	protein kinase DIBA 03/2015 - 05/2014
2	Antineoplastic Agents (Antineoplastics)IBA 07/2013 - 04/2005
2	Panitumumab (Vectibix)FDA Link 12/2010 - 05/2006
2	Growth Factor ReceptorsIBA 05/2010 - 10/2007
2	Monoclonal AntibodiesIBA 10/2007 - 04/2006
2	Alkylating AgentsIBA 01/2006 - 03/2005
1	Calcibiotic Root Canal SealerIBA 03/2024
1	Dextran SulfateIBA 03/2024
1	AntibodiesIBA 07/2023
1	Aurora Kinase AIBA 07/2023
1	Fulvestrant (Faslodex)FDA Link 07/2023
1	Sorafenib (BAY 43-9006)FDA Link 07/2023
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 07/2023
1	Tamoxifen FDA LinkGeneric 07/2023
1	Taxoids (Taxanes)IBA 07/2023
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 07/2023
1	osimertinibIBA 07/2023
1	Focal Adhesion Protein-Tyrosine KinasesIBA 02/2023
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 02/2023
1	VaccinesIBA 01/2023
1	Ad26COVS1IBA 01/2023
1	mRNA VaccinesIBA 01/2023
1	snake venom protein C activatorIBA 01/2023
1	COVID-19 VaccinesIBA 01/2023
1	QuassinsIBA 01/2023
1	Opioid Analgesics (Opioids)IBA 01/2022
1	pembrolizumabIBA 01/2022
1	PlatinumIBA 01/2022
1	Azacitidine (5 Azacytidine)FDA Link 01/2022

Therapy/Procedure

31	Therapeutics 07/2023 - 02/2004
28	Drug Therapy (Chemotherapy) 01/2023 - 01/2000
13	Palliative Care (Palliative Therapy) 01/2023 - 03/2014
5	Adjuvant Chemotherapy 01/2017 - 11/2002
3	Precision Medicine 07/2023 - 08/2013
2	Complementary Therapies (Alternative Medicine) 01/2019 - 11/2017
2	Combination Drug Therapy (Combination Chemotherapy) 01/2016 - 11/2008
1	Immunomodulation 01/2022